Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763664 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Syndecan-2 plays a pivotal role in colon cancer cell migration. ⺠Deletion of the EFYA sequence at the C-terminal of the cytoplasmic domain abolished syndecan-2-mediated cell migration and syndecan-2 interaction with syntenin-1. ⺠Syntenin-1 expression potentiated colon cancer cell migration induced by syndecan-2, and syndecan-2-mediated cell migration was reduced when syntenin-1 expression was diminished. ⺠Syndecan-2 cytoplasmic domain regulates colon cancer cell migration via interaction with syntenin-1.
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Authors
Hawon Lee, Yeonhee Kim, Youngsil Choi, Sojoong Choi, Eunkyung Hong, Eok-Soo Oh,