| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763683 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠IDH1 and IDH2 mutations are not detected in the rat C6 glioma cell line model. ⺠IDH2 mutations are not required for the tumorigenesis of glioma. ⺠IDH2R172G can sensitize glioma sensitivity to chemotherapy through NADPH levels. ⺠IDH2R172G can give a benefit to traditional chemotherapy of glioma. ⺠This finding serves as an important complement to existing research on this topic.
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Authors
Yuejun Fu, Rui Huang, Yali Zheng, Zhiyun Zhang, Aihua Liang,