Article ID Journal Published Year Pages File Type
10763692 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► TRIM22 selectively activates NF-κB. ► TRIM22-mediated NF-κB activation is dependent on its RING domain and SPRY domain. ► TRIM22 stimulates U937 cells to secret pro-inflammatory cytokines. ► The induction of pro-inflammatory cytokines by TRIM22 is dependent on its effect on NF-κB activity.
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Authors
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