Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763692 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠TRIM22 selectively activates NF-κB. ⺠TRIM22-mediated NF-κB activation is dependent on its RING domain and SPRY domain. ⺠TRIM22 stimulates U937 cells to secret pro-inflammatory cytokines. ⺠The induction of pro-inflammatory cytokines by TRIM22 is dependent on its effect on NF-κB activity.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Shanshan Yu, Bo Gao, Zhijian Duan, Wei Xu, Sidong Xiong,