| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763707 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠The mouse Slc39a8 gene encodes the ZIP8 transporter. ⺠ZIP8 functions endogenously as a electroneutral Zn2+/(HCO3-)2 symporter. ⺠A Slc39a8(neo/neo) hypomorph mouse, due to retention of the neo mini-gene, has been created. ⺠ZIP8 expression in utero is â¼90% decreased in all tissues examined. ⺠This mouse model will be useful for studying developmental and in utero physiological functions of ZIP8.
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Authors
Bin Wang, Lei He, Hongbin Dong, Timothy P. Dalton, Daniel W. Nebert,