Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763716 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Fetal liver was separated into hepatoblasts, endothelial cells and hematopoietic cells by flow cytometry. ⺠Dlk-1-expressing hepatoblasts primarily expressed EPO and SCF by real-time PCR and ELISA analysis. ⺠EPO and SCF expressions were down-regulated in Map2k4â/â fetal liver which lacks hepatoblasts. ⺠Hepatoblasts comprise a niche for fetal liver erythropoiesis.
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Authors
Daisuke Sugiyama, Kasem Kulkeaw, Chiyo Mizuochi, Yuka Horio, Satoko Okayama,