Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763717 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Ca2+ entry through the L-subtype of VDCCs selectively regulate the endocytotic response after the application of a depolarizing pulse. ⺠L channel blockade with nifedipine transformed the exocytotic responses elicited by a double-pulse protocol, from depression to facilitation. ⺠This effect was mimicked by dynasore, calmidazolium, GTP-γS and GDP-βS. ⺠Ca2+ entry through PQ regulates fast exocytosis while Ca2+ entry through L channels preferentially controls rapid endocytosis.
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Authors
Juliana M. Rosa, Marina Conde, Carmen Nanclares, Angela Orozco, Inés Colmena, Ricardo de Pascual, Antonio G. GarcÃa, Luis GandÃa,