Article ID Journal Published Year Pages File Type
10763766 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► Depletion of cellular PABP level arrests mRNA translation in HeLa cells. ► PABP knock down leads to apoptotic cell death. ► PABP depletion does not affect transcription. ► PABP depletion does not lead to nuclear accumulation of mRNA.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Depletion of cellular poly (A) binding protein prevents protein synthesis and leads to apoptosis in HeLa cells
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