Article ID Journal Published Year Pages File Type
10763794 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► Lipid peroxidation and tyrosine nitration are elevated in the adrenal medulla of aged rats. ► Endogenous antioxidant enzymes are depleted in the hypothalamus of very old rats. ► Caloric restriction (40%) prevents the accumulation of 4-HNE in the adrenal medulla of aged rats and attenuates the age-related reduction in antioxidant enzymes in the hypothalamus.
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