Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10763794 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Lipid peroxidation and tyrosine nitration are elevated in the adrenal medulla of aged rats. ⺠Endogenous antioxidant enzymes are depleted in the hypothalamus of very old rats. ⺠Caloric restriction (40%) prevents the accumulation of 4-HNE in the adrenal medulla of aged rats and attenuates the age-related reduction in antioxidant enzymes in the hypothalamus.
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Authors
Melissa A. Whidden, Nataliya Kirichenko, Zekai Halici, Benedek Erdos, Thomas C. Foster, Nihal Tümer,