| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763805 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠The reverse transcriptase (RT) of HIV-1 has a non-templated addition activity. ⺠RT has also a clamp activity that allows template switches while synthesizing DNA. ⺠This clamp depends on a complementarity between the primer tails and template strands. ⺠We studied how parameters of these two activities affect the RT's DNA strand switches. ⺠dNTP bias, proper acceptor strands presence and the duplex stabilities were studied.
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Authors
Iris Oz-Gleenberg, Amnon Hizi,