| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763810 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Knockdown of PARP-1 suppresses the LPS-induced expression of caspase-11. ⺠Knockdown of PARP-1 suppresses the caspase-11 promoter activity following LPS stimulation. ⺠PARP-1 is recruited to the caspase-11 promoter region containing NF-κB-binding sites following LPS stimulation. ⺠PARP-1 inhibitors cannot suppress the caspase-11 induction. ⺠PARP-1 does not suppress IFN-γ-induced expression of caspase-11.
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Authors
Lang Yoo, Seokheon Hong, Ki Soon Shin, Shin Jung Kang,