Article ID Journal Published Year Pages File Type
10763813 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► Let-7/Fas form a double-negative feedback loop which regulates Fas-mediated apoptosis. ► Fas activation suppresses Dicer processing and let-7 microRNA biogenesis. ► Let-7 inhibitor sensitizes colon carcinoma cells to Fas-related apoptosis.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
A let-7/Fas double-negative feedback loop regulates human colon carcinoma cells sensitivity to Fas-related apoptosis
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