| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763876 | Biochemical and Biophysical Research Communications | 2011 | 8 Pages |
Abstract
⺠Human eosinophils express CCR8. ⺠Human eosinophils respond to CCL1. ⺠Mature T cells produce CCL1 which in an autocrine fashion desensitize them. ⺠Novel CCR8 antagonist inhibits functional response in eosinophils and T cells. ⺠Small molecule CCR8 compounds show either agonistic or antagonistic activity.
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Authors
Anna K.C. Karlsson, Katarina Walles, HÃ¥kan Bladh, Stephen Connolly, Marco Skrinjar, Alexander Rosendahl,