| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763922 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠The absence of TLR4 is associated with reduced endothelial cell function in mesenteric arteries. ⺠TLR4â/â mouse arteries have reduced acetylcholine responses. ⺠TLR4â/â have increased superoxide levels when stimulated with acetylcholine. ⺠An increase in superoxide generation reduces the activity of endothelial derived nitric oxide.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Louise S. Harrington, Martina H. Lundberg, Michael Waight, Adrian Rozario, Jane A. Mitchell,