| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763932 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠We investigate the human cancer-associated antigen recognized by antibody AE3 using carbohydrate microarrays. ⺠We find that is expressed on glycolipid as well as on mucin-type glycoproteins. ⺠AE3 has strong selectivity for the carbohydrate moiety of the sulfoglycolipid SM1a. ⺠Assignment of a discrete carbohydrate sequence as a cancer-associated antigen opens the way to its exploration as a novel biomarker.
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Authors
Angelina S. Palma, Yan Liu, Robert A. Childs, Colin Herbert, Denong Wang, Wengang Chai, Ten Feizi,