| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763960 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠We examined CTL immunodominance after SIV challenge in vaccinated macaques. ⺠Vaccine antigen-specific CTL responses were induced dominantly post-challenge. ⺠SIV non-vaccine antigen-specific CTL induction post-challenge was delayed. ⺠These imply an influence of vaccination on immunodominance post-viral exposure. ⺠This study provides insights into CTL antigen design in AIDS vaccine development.
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Authors
Yusuke Takahara, Saori Matsuoka, Tetsuya Kuwano, Tetsuo Tsukamoto, Hiroyuki Yamamoto, Hiroshi Ishii, Tadashi Nakasone, Akiko Takeda, Makoto Inoue, Akihiro Iida, Hiroto Hara, Tsugumine Shu, Mamoru Hasegawa, Hiromi Sakawaki, Mariko Horiike, Tomoyuki Miura,