Article ID Journal Published Year Pages File Type
10763970 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► We synthesized SPA0537, a benzothiazole analog. ► SPA0537 is a potent NF-κB inhibitor. ► SPA0537 suppresses the production of proinflammatory mediators in human rheumatoid fibroblast-like synoviocytes. ► SPA0537 is effective at suppressing osteoclast differentiation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Inhibition of TNF-α-mediated inflammatory responses by a benzodioxolylacetylamino-linked benzothiazole analog in human fibroblast-like synoviocytes
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