| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10763992 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠ITSN2 long isoform (ITSN2-L) is involved in Xenopus early embryonic development. ⺠Embryos expressing the C-terminal extension of ITSN2-L demonstrated gastrulation arrest. ⺠The DH-PH tandem of ITSN2-L colocalized with actin and affected actin polymerization in embryos. ⺠Developmental defects induced by microinjection of DH-PH mRNA depended on the activity of Cdc42.
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Authors
Olga Novokhatska, Mykola Dergai, Nathalie Houssin, Liudmyla Tsyba, Jacques Moreau, Alla Rynditch,