| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764010 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠nNOS knockout mice exhibit mild impairments in object recognition memory. ⺠nNOS knockout mice display working memory deficits, potential impairments in prefrontal cortical functioning. ⺠nNOS interacts with DISC1, another genetic risk factor for schizophrenia that plays roles for cortical development and prefrontal cortex functioning, in the developing cerebral cortex. ⺠DISC1-NDEL1 interaction is increased in nNOS knockout mice. ⺠nNOS knockout mice are useful tools in studying the role of nNOS signaling in cortical development and prefrontal cortical functioning.
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Authors
Sandra P. Zoubovsky, Vladimir M. Pogorelov, Yu Taniguchi, Sun-Hong Kim, Peter Yoon, Evaristus Nwulia, Akira Sawa, Mikhail V. Pletnikov, Atsushi Kamiya,