Article ID Journal Published Year Pages File Type
10764019 Biochemical and Biophysical Research Communications 2010 6 Pages PDF
Abstract
► BMP-4 promotes osteocalcin synthesis in osteoblast-like cells. ► PKC plays an important role in BMP-4-mediated osteocalcin synthesis. ► PKC βII and PKC δ/θ regulates osteoblastic differentiation and mineralization. ► PKCs are involved in BMP-4-mediated VEGF production.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Protein kinase C βII and δ/θ play critical roles in bone morphogenic protein-4-stimulated osteoblastic differentiation of MC3T3-E1 cells
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