Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764020 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠TAp73 is expressed in neural stem cells and its expression increases following their differentiation. ⺠Neural stem cells from p73 null mice have a reduced proliferative potential. ⺠p73-deficient neural stem cells show reduced expression of members of the Sox-2 and Notch gene families. ⺠Neurogenic areas are reduced in the brains of embryonic and adult p73â/â mice.
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Authors
Massimiliano Agostini, Paola Tucci, Hailan Chen, Richard A. Knight, Daniele Bano, Pierluigi Nicotera, Frank McKeon, Gerry Melino,