Article ID Journal Published Year Pages File Type
10764029 Biochemical and Biophysical Research Communications 2010 4 Pages PDF
Abstract
► GPR40 mediates the short-term effects of FFAs on GSIS through the role of PDX-1 and GLUT2. ► GPR40 does not mediate the chronic toxic effects of FFAs on β-cell function. ► The reverse role of pioglitazone on lipotoxicity of β-cells may be related with GPR40.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The relationship between GPR40 and lipotoxicity of the pancreatic β-cells as well as the effect of pioglitazone
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