| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764035 | Biochemical and Biophysical Research Communications | 2010 | 7 Pages |
Abstract
⺠Our findings provide the first evidence that orexin-A, a neuropeptide originally discovered in the hypothalamus, stimulates angiogenesis in vivo and in vitro. ⺠We demonstrated the presence of orexin receptors, OX1R and OX2R, on the vascular endothelial cells. ⺠We found that orexin-A-induced angiogenesis requires MEK/ERK-dependent signaling pathway.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Mi-Kyoung Kim, Hyun-Joo Park, Su-Ryun Kim, Yoon Kyung Choi, Hwa Kyoung Shin, Jae-Hoon Jeon, Hye-Ock Jang, Il Yun, Soo-Kyung Bae, Moon-Kyoung Bae,