| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764048 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠Akt-activated p21 was primarily expressed in cytoplasm of cells in transgenic mice. ⺠Akt-activated p21 accelerated tumor onset in MMTV/neu mice. ⺠Akt-activated p21 promoted lung metastasis in MMTV/neu mice. ⺠In vivo evidence that cytoplasmic p21 functions as an oncogene.
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Authors
Xiaoyun Cheng, Weiya Xia, Jer-Yen Yang, Jennifer L. Hsu, Chao-Kai Chou, Hui-Lung Sun, Shannon L. Wyszomierski, Gordon B. Mills, William J. Muller, Dihua Yu, Mien-Chie Hung,