| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764070 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠Filovirus glycoprotein (GP) having a deficient receptor binding region were generated. ⺠Mutant GPs mediated virus entry less efficiently than wild-type GP. ⺠Mutant GPs bound to C-type lectins but not mediated entire steps of cellular entry. ⺠C-type lectins do not independently mediate filovirus entry into cells. ⺠Other molecule(s) are required for C-type lectin-mediated entry of filoviruses.
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Authors
Keita Matsuno, Eri Nakayama, Osamu Noyori, Andrea Marzi, Hideki Ebihara, Tatsuro Irimura, Heinz Feldmann, Ayato Takada,