Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764082 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. ⺠miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. ⺠miR-132 and miR-212 expression is increased by a β2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression.
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Authors
Jong-Kook Park, Jon C. Henry, Jinmai Jiang, Christine Esau, Yuriy Gusev, Megan R. Lerner, Russell G. Postier, Daniel J. Brackett, Thomas D. Schmittgen,