Article ID Journal Published Year Pages File Type
10764086 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► Higher expression levels of LAMB3 and LAMC2 mRNA in tumor tissues than in normal tissues. ► DNA hypomethylation was associated with the up-regulation of both genes. ► Treatment with a methylation inhibitor induces LAMB3 and LAMC2 expression in gastric cancer cell lines. ► Histone modification is associated with the expression of both genes. ► The expression level of LAMB3 affects multiple malignant phenotypes in gastric cancer cell lines.
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