Article ID Journal Published Year Pages File Type
10764106 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► In this study, we investigated the effects of leptin on adipocyte differentiation prepared from subcutaneous fat of TallyHo mice. ► Leptin inhibited the adipocytes differentiation at physiological concentration via inhibition of PPARγ expression. ► Inhibitors of ERK and STAT1 restored the leptin's inhibitory activity both in vitro and in vivo.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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