Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764106 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠In this study, we investigated the effects of leptin on adipocyte differentiation prepared from subcutaneous fat of TallyHo mice. ⺠Leptin inhibited the adipocytes differentiation at physiological concentration via inhibition of PPARγ expression. ⺠Inhibitors of ERK and STAT1 restored the leptin's inhibitory activity both in vitro and in vivo.
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Authors
Ki Young Kim, Joo Young Kim, Yoon-Young Sung, Won Hoon Jung, Hee-Youn Kim, Ji Seon Park, Hyae Gyeong Cheon, Sang Dal Rhee,