| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764119 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Up to 80% of patients with advanced cancers are affected by cancer cachexia accounting for nearly 30% of cancer-related deaths. ⺠The toxicity of chemotherapeutic drugs in normal cells is a serious problem with significant side effects on cancer treatment. ⺠The flavonoid quercetin inhibits tumors growth and increases survival and prevention of cachexia in Walker 256 tumor-bearing rats. ⺠Decrease of MMP-2 and VEGF levels strongly support the anticancer function of quercetin.
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Authors
Camila A. Camargo, Maria Eleonora F. da Silva, Rodrigo A. da Silva, Giselle Z. Justo, Maria Cristina C. Gomes-Marcondes, Hiroshi Aoyama,