| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764151 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Divalent metal cation binds to chondroitin sulfate with different efficiencies. ⺠Chondroitin sulfate metal salts as donors regulate hyaluronidase transglycosylation. ⺠Barium enhances the transglycosylation of hyaluronidase. ⺠Zinc inhibits the transglycosylation of hyaluronidase. ⺠Strong inhibitory effect of zinc is recovered by addition of EDTA.
Keywords
HPAEC-PADHEPGalNGalNAcN-acetylgalactosamineGAGGlcUAGlcNBTHDERGlcNAcC4SC6SGlucuronic acidTransglycosylationDermatan sulfateHeparin sulfateMetalN-acetylglucosamineHeparinHyaluronanHyaluronidasebovine testicular hyaluronidaseCationhigh performance anion exchange chromatography with pulsed amperometric detectionChondroitinchondroitin 4-sulfateChondroitin 6-sulfateChondroitin sulfateGalactosamineglucosamineGlycosaminoglycan
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Authors
Ikuko Kakizaki, Isoshi Nukatsuka, Keiichi Takagaki, Mitsuo Majima, Mito Iwafune, Shinichiro Suto, Masahiko Endo,