| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764172 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠PCOOH induced THP-1 cell adhesion to ICAM-1 via F-actin rich protrusion formation. ⺠Isoprenoid depletion abrogated the PCOOH-induced actin reorganization and subsequent cell adhesion. ⺠PCOOH activated Rac GTPases (Rac1 and Rac2). ⺠Inhibition of Rac function led to decreased protrusion formation and cell adhesion in PCOOH-treated cells.
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Authors
Akira Asai, Fumitaka Okajima, Yasushi Nakajima, Mototsugu Nagao, Kiyotaka Nakagawa, Teruo Miyazawa, Shinichi Oikawa,