| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764186 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Nrf2 anti-oxidant function is impaired when HDAC activity is inhibited. ⺠HDAC inhibition decreases Nrf2 protein stability. ⺠HDAC2 is involved in reduced Nrf2 stability and both correlate in COPD samples. ⺠HDAC inhibition increases Nrf2 acetylation.
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Authors
Nicolas Mercado, Rajesh Thimmulappa, Catherine M.R. Thomas, Peter S. Fenwick, Kirandeep K. Chana, Louise E. Donnelly, Shyam Biswal, Kazuhiro Ito, Peter J. Barnes,