Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764223 | Biochemical and Biophysical Research Communications | 2010 | 7 Pages |
Abstract
⺠FGF2 induces an osteocyte-like phenotype in osteoblasts and stromal cells. ⺠FGF2 dramatically increases gene expression of DMP1. ⺠FGF2 suppression of SOST may contribute to the osteoanabolic effect of FGF2 in vivo. ⺠DMP1 and E11 expression precedes the formation of osteocyte-like cell processes. ⺠Model to study osteocyte biology to complement cell lines, such as MLO-Y4 cells.
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Authors
Rishi R. Gupta, David J. Yoo, Carla Hebert, Corinne Niger, Joseph P. Stains,