| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764292 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠GSA-ATBsu exits as the double PMP form in solution without the exotic cofactor addition after purification. ⺠GSA-ATBsu structure shows the symmetry at the open gating loop region as well as identical cofactor (PMP) binding in each monomer. ⺠GSA-ATBsu structure supports one reaction mechanism suggested for this enzyme. ⺠The symmetry of GSA-ATBsu structure challenges the previously proposed negative cooperativity between monomers of this enzyme.
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Authors
Honghua Ge, Xinhuai Lv, Jun Fan, Yongxiang Gao, Maikun Teng, Liwen Niu,