| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764296 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠PcyA catalyzes the reduction of the biliverdin IXα. ⺠Structure of PcyA V225D protein revealed the gross changes of the substrate-binding pocket. ⺠Induced-fit did not occur unlike wild-type PcyA upon substrate binding to the V225D protein. ⺠Binding manner of the substrate in V225D was entirely different from that in wild-type PcyA.
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Authors
Kei Wada, Yoshinori Hagiwara, Yuko Yutani, Keiichi Fukuyama,