| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764352 | Biochemical and Biophysical Research Communications | 2010 | 4 Pages |
Abstract
⺠LANA specifically binds to p53 via DNA binding domain. ⺠Polyubiquitylation of p53 in the presence of LANA was obviously enhanced. ⺠LANA also interacts with Cullin 5 and Rbx1, active subunit of E3 ubiquitin ligase complex. ⺠LANA functions in the regulation of p53, consequently contributing to maintenance of latency.
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Authors
Tohru Suzuki, Tomoyasu Isobe, Masatoshi Kitagawa, Keiji Ueda,