| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764355 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠MiR-15a/16-1 sensitizes ATO-induced apoptosis in K562 cells. ⺠MiR-15a/16-1 and ATO synergistically induce mitochondrial dysfunction and activation of caspase-3. ⺠MiR-15a/16-1 and/or ATO do not affect the level of Bcr-Abl expression. ⺠MiR-15a/16-1 and ATO synergistically induce apoptosis in leukemic cells.
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Authors
Shen-meng Gao, Chiqi Chen, Jianbo Wu, Yanxia Tan, Kang Yu, Chong-Yun Xing, Aifang Ye, Lihui Yin, Lei Jiang,