| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764384 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Although multiple compartmentalization of HO-1 has been documented, the functional implication of this enzyme at these subcellular organelles is only partially elucidated. ⺠HO-1 expression at ER is induced by a diverse set of conditions that cause ER stressors. ⺠CO may induce HO-1 expression in human ECs by activating Nrf2 through PERK phosphorylation in a positive-feedback manner. ⺠ER-residing HO-1 and its cytoprotective activity against ER stress is discussed.
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Authors
Hong Pyo Kim, Hyun-Ock Pae, Sung Hun Back, Su Wol Chung, Je Moon Woo, Yong Son, Hun-Taeg Chung,