| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764387 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Inhibition of the production of Aβ is a widely pursed strategy for the treatment for Alzheimer's disease. ⺠β-Secretase and γ-secretase, which produce Aβ, are obvious targets for potential drugs that inhibit their activity. ⺠Modulation of APP processing without interfering with other signaling is an important therapeutic goal for the development of a secretase regulator. ⺠Two or more therapeutic approaches might ultimately be combined for greater success.
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Authors
Ha-Na Woo, Sang-Ha Baik, Jong-Sung Park, A-Ryeong Gwon, Sunghee Yang, Young-Kwang Yun, Dong-Gyu Jo,