Article ID Journal Published Year Pages File Type
10764389 Biochemical and Biophysical Research Communications 2011 7 Pages PDF
Abstract
► Human islets are enriched in miR-375, miR-127-3p and miR-184. ► Expression of miR-375, miR-122, miR-127-3p and miR-184 is positively correlated to insulin biosynthesis. ► Levels of miR-127-3p and miR-184 are negatively correlated to glucose-stimulated insulin secretion. ► These correlations are diminished in islets of glucose-intolerant donors.
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