| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764429 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠ALR decreases cytochrome c release from mitochondria. ⺠ALR protects hepatocytes against apoptosis induction by ethanol, TRAIL, anti-Apo, TGF-β and actinomycin D. ⺠ALR exerts a liver-specific anti-apoptotic effect. ⺠A possible medical usage of ALR regarding protection of liver cells during apoptosis inducing therapies.
Keywords
HGFFACSTGF-βLPSERK-1/2EGFNEAAPHHMTSFCS3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazoliumprimary human hepatocytesactinomycin DLiver regenerationTransforming Growth Factor BetaAugmenter of liver regenerationfetal calf serumAnti-apoptosisepidermal growth factorHepatocyte growth factorfluorescence activated cell sortingAct DTRAILlipopolysaccharideHuman hepatocytesmitogen-activated protein kinase kinaseMAP kinase
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Authors
Maren Ilowski, Axel Kleespies, Enrico N. de Toni, Barbara Donabauer, Karl-Walter Jauch, Jan G. Hengstler, Wolfgang E. Thasler,