| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764431 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Actin was detected at the centrosome with the anti-actin antibody 1C7 that recognizes antiparallel (“lower dimer”) actin dimers. ⺠Centrosomal actin was found in interphase but not mitotic MDA-MB-231 cells. ⺠Neither the anti-actin antibody C4 that binds to globular, monomer actin, nor the anti-actin antibody 2G2 that recognizes the nuclear conformation of actin detect actin at the centrosome. ⺠The Arp2/3 complex transiently localizes at the pericentriolar matrix but not at the centrioles of interphase HEK 293T cells.
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Authors
Thomas Hubert, Joël Vandekerckhove, Jan Gettemans,