Article ID Journal Published Year Pages File Type
10764457 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► EGCG ameliorates the GJIC-inhibitory effect of serum deprivation. ► Recovery of GJIC activity by EGCG depends on Cx43. ► EGCG activates MAPK and PI3K/Akt/eNOS pathway. ► EGCG improves Cx43 gap junction via the activation of ERK MAPK.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Down-regulation of connexin43 gap junction by serum deprivation in human endothelial cells was improved by (−)-Epigallocatechin gallate via ERK MAP kinase pathway
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