| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764475 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠A novel lipase, Nceh1 is involved in the cholesterol homeostasis in adrenal glands. ⺠Nceh1 and Lipe are the major cholesterol ester hydrolases in adrenal glands. ⺠Deficiency of Nceh1 and/or Lipe causes lipid accumulation in adrenal glands ⺠Deficiency of these two lipases causes adrenal enlargement. ⺠Deficiency of the lipases does not affect ACTH-stimulated corticosterone secretion.
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Authors
Keisuke Ohta, Motohiro Sekiya, Hiroshi Uozaki, Masaki Igarashi, Satoru Takase, Masayoshi Kumagai, Mikio Takanashi, Yoshinori Takeuchi, Yoshihiko Izumida, Midori Kubota, Makiko Nishi, Hiroaki Okazaki, Yoko Iizuka, Naoya Yahagi, Hiroaki Yagyu,