| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764477 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Th2 cytokines and their downstream JAK-STAT pathways play a critical role in asthma. ⺠A JAK inhibitor pyridone 6 was encapsulated in nanoparticles. ⺠We studied the effects of pyridone 6 on asthmatic responses in a mouse model. ⺠Pyridone 6 treatment during allergen challenge suppressed asthmatic responses.
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Authors
Yuko Matsunaga, Hiromasa Inoue, Satoru Fukuyama, Hideyuki Yoshida, Atsushi Moriwaki, Takafumi Matsumoto, Koichiro Matsumoto, Yukari Asai, Masato Kubo, Akihiko Yoshimura, Yoichi Nakanishi,