Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764484 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠We employ the human HT29 cell line as a model, and purify a population of colon CSCs expressing a CD133 surface phenotype by FACS. ⺠The CD133+ cells exhibit stem-like features including expression of “stemness” genes as well as self-renewal and differentiation capacity. ⺠We reveal the miRNA expression signature characteristic of colon cancer stem cells for the first time.
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Authors
Huanle Zhang, Weihua Li, Feifei Nan, Fang Ren, Hongxia Wang, Yingchun Xu, Fengchun Zhang,