| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764489 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠The proteasome inhibitor MG132 increases the levels of both endogenous and exogenous DLC1 proteins in HEK293 and Hep3B cells. ⺠DLC1 is an unstable protein that is degraded by the 26S proteasome in Hep3B cells. ⺠Five putative PEST motifs are located in the N-terminus of DLC1. ⺠Deletion of the PEST motifs decreases the intracellular stability of the N-terminus of DLC1.
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Authors
Hong-wei Luo, Qiu-ping Luo, Ying Yuan, Xiao-ying Zhu, Shi-feng Huang, Zhi Peng, Chun-li Li, Zong-gan Huang, Wen-li Feng,