Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764537 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠First report to demonstrate an in vivo expression system of an ABC multidrug transporter CgCdr1p of C. glabrata. ⺠First report on the structure and functional characterization of CgCdr1p. ⺠Functional conservation of divergent but typical residues of CgCdr1p. ⺠CgCdr1p elicits promiscuity towards substrates and has a large drug binding pocket with overlapping specificities.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Nidhi Puri, Raman Manoharlal, Monika Sharma, Dominique Sanglard, Rajendra Prasad,