| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764556 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Crystal structure of botulinum C-D mosaic neurotoxin at 1.56 Ã
resolution. ⺠BoNT/CD-HCR binds PE liposomes more tightly than BoNT/D-HCR. ⺠Lysine-1118 may enhance BoNT/CD-HCR synaptosome binding by stabilizing a putative membrane interaction loop. ⺠Binding of a sulfate ion to K1136 may reflect natural interactions of BoNT/CD-HCR with membrane phospholipids or glycolipids.
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Authors
Yanfeng Zhang, Garry W. Buchko, Ling Qin, Howard Robinson, Susan M. Varnum,