| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764561 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Ectopic expression of NuSAP lead to mitotic arrest observably dependent on the kinase activity of ATM. ⺠ATM interacts with NuSAP and phosphorylates NuSAP on Ser124. The phosphorylation and interaction occur specifically at G2/M-phase. ⺠Our work has uncovered an ATM-dependent checkpoint pathway that prevents mitotic progression by targeting a microtubule-associated protein, NuSAP.
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Authors
Ping Xie, Lu Li, Guichun Xing, Chunyan Tian, Yuxin Yin, Fuchu He, Lingqiang Zhang,