Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764567 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠RIG-I and MDA5 are expressed in conjunctival epithelium. ⺠RIG-I and MDA5 are up-regulated by polyI:C stimulation in conjunctival epithelium. ⺠IPS-1 contributes to innate immune responses in conjunctival epithelial cells.
Keywords
ICAM-1IPS-1NLRsRSAD2RLRschemokine (C–C motif) ligandchemokine (C–X–C motif) ligandTSLPMDA5RIG-ICXCLTLR3CCLPAMPsNODPolyI:CTLRspathogen-associated molecular patternsconjunctival epitheliuminterferonIFNnucleotide-binding oligomerization domainThymic stromal lymphopoietinintercellular adhesion molecule-1Polyinosinic:polycytidylic acidretinoic acid-inducible gene-IToll-like receptors
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Authors
Mayumi Ueta, Taro Kawai, Norihiko Yokoi, Shizuo Akira, Shigeru Kinoshita,